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2018 Annual Texas Drug Discovery Symposium

April 12 @ 8:00 am - April 13 @ 5:00 pm

| Free

cidd2018symposium

The Center for Innovative Drug Discovery, a partnership between UT Health SA and UTSA, will hold its 3rd annual Drug Discovery Symposium on April 12-13 at the Greehey Children’s Cancer Research Institute on the north campus of UT Health at San Antonio.

Symposium Agenda:

  • Presentations by national speakers from academic and industry and local researchers engaged in drug discovery and drug development
  • Topics include target discovery and validation, non-druggable targets, novel technologies
  • Drug discovery tools and technologies available in San Antonio
  • Poster and networking sessions

Plenary Keynote Presentation:
screen-shot-2018-02-26-at-3-36-16-pm

 

Lawrence Goldstein, PhD
Distinguished Professor, Depts. of Cellular and Molecular Medicine and Neurosciences
Director, UC San Diego Stem Cell Program
Scientific Director, Sanford Consortium for Regenerative Medicine
Director, Sanford Stem Cell Clinical Center, UCSD School of Medicine

 

 

Session One:  Novel Approaches to Target Identification
Session Chair:  Stanton McHardy, PhD

Jenny Hsieh, PhD, Precision Models of Brain Disorders for Drug Discovery
Marty Matzuk
, MD, PhD, Baylor College of Medicine, DNA encoded libraries
Daniel Nomura, PhD, UC Berkeley, TBD

*
Session Two:  Addressing Challenging Drug Targets       

Session Chair:  Matthew J. Hart, PhD

Kevin Dalby, PhD, UT Austin, Discovery of a Novel ERK Inhibitor with Activity in BRAF Mutant Melanoma Models
Gorfe Alemayehu
, PhD, University of Texas Medical School, Houston,
Karen Vasquez, PhD, UT Austin, Molecular probes to interrogate roles of non-B DNA structures in DNA damage and genetic instability

*
Session Three
Screening and Target Discovery at UT Health San Antonio/UTSA
Session Chair: Bruce Nicholson, PhD

Rong Li, PhD, UT Health San Antonio, Rallying the Antitumor Activity of Estrogen Receptor beta
Paul Hasty, PhD, UT Health San Antonio, TREX2 inhibitors reduce the level of mutations in cells defective for homologous recombination and mismatch repair
Stan McHardy, PhD, UTSA, Synthesis and SAR of New Natural Product-Based Diaryloxazoles with Selective Activity against Androgen Receptor-Positive Breast Cancer Cells

*
Session Four: Neurological Disease
Session Chair:  Stanton McHardy, PhD

Jotham Coe, PhD, Pfizer, Nicotine Meet’s its Match? . . . The Discovery of Varenicline
Ivy Carroll, PhD, RTI International, Design, Synthesis and In Vitro Pharmacological Evaluation of Novel Kappa Opioid Receptor Antagonists
Adron Harris, PhD, UT Austin, Transcriptomic and Bioinformatic Approaches for Pharmacotherapy of Alcohol Use Disorders

*
Session Five
:
Oncology and Immuno-Oncology
Session Chair: Rong Li, PhD

Brian Blagg, PhD, Notre Dame University, Targeting the Hsp90 Molecular Chaperone for the Treatment of Cancer and Other Diseases
Jim Rizzi
, PhD, Peleton, Discovery of PT2385, a first-in-class HIF-2α inhibitor for the treatment of renal cell carcinoma
Tyler Curiel,
MD, UT Health San Antonio, Tumor cell-intrinsic Ig superfamily signals as novel cancer drug discovery targets: PD-L1/PD-1 signals as the test case
Alex Pertsemlidis, PhD, UT Health SA, GCCRI, Title

*
Session Six: Cardiovascular and Metabolic Diseases
Session Chair: Hua-Yu Wang, PhD

Stefano Tiziani, PhD, UT Austin, High-content metabolomic screening in biomarker discovery and therapeutic treatment
Harshini Neelakantan, PhD, UT Medical Branch, Small molecule NNMT inhibitors: An adipose-centric approach to combat metabolic diseases

*

Closing Remarks:
Bruce Nicholson, PhD
Director, Center for Innovative Drug Discovery
Chairman, Department of Biochemistry and Structural Biology
UT Health San Antonio

To register:  ** REGISTRATION IS FULL **

>> Download Agenda
>> Download Symposium Flyer
>> Download Local Accommodations
>> View UT Health SA Greehey campus (Map)

Local Accommodations:

  1. Hyatt Place San Antonio Northwest/Medical Center (Rooms blocked for CIDD Conference.)  **Note: has shuttle service to the Symposium at Greehey Children’s Cancer Research Institute
  2. Drury Inn & Suites Northwest Medical Center
  3. Omni San Antonio Hotel at the Colonnade
  4. Homewood Suites Northwest San Antonio Hotel
  5. Embassy Suites – San Antonio Texas Hotel on NW I-10
  6. La Quinta San Antonio Medical Center
  7. Courtyard Mariott

 

Contact Symposium Co-Chairs:
Matt Hart, Ph.D., Director, Center for Innovative Drug Discovery High Throughput Screening Core Facility, UT Health SA.
Stanton F. McHardy, Ph.D., Co-Director, Center for Innovative Drug Discovery, Director, Max and Minnie Tomerlin Voelcker Medicinal Chemistry Core Facility, UTSA

Details

Start:
April 12 @ 8:00 am
End:
April 13 @ 5:00 pm
Cost:
Free

Organizer

The Center For Innovative Drug Discovery
Email:
stanton.mchardy@utsa.edu
Website:
http://www.cidd.uthscsa.edu/

Venue

Greehey Children’s Cancer Research Institute
8403 Floyd Curl Dr.
San Antonio, TX 78229 United States
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