Genomics Core

Examine gene and protein expression within tissue context. Spatial transcriptomics and proteomics preserve tissue architecture to investigate cellular organization, microenvironment interactions, and molecular heterogeneity with spatial resolution.

Resources: Visium CytAssist • NanoString GeoMx

Explore cellular heterogeneity with transcriptomic, epigenomic, and proteomic profiling at single-cell resolution. Single cell multiomics enables investigation of complex cell populations, cellular states, and molecular mechanisms that are masked in bulk analyses. 

Resources: Chromium X • Evercode • PIPseq • TotalSeq

Quantify protein expression at single cell resolution using conventional Western blot antibodies. This technology enables to measure cell signaling pathway activity and protein expression across individual cells which may be masked in bulk analyses.

Resources: Bio-Techne Milo

Transcriptome profiling for coding and non-coding RNA, enabling gene expression studies, biomarker discovery, pathway analysis, and splicing variants identification. Our flexible workflow supports mRNA, total RNA, and small RNA sequencing.

Resources: Illumina-compatible Total RNA-seq • mRNA-seq • MicroRNA Sequencing

Study genomes for sequence variation, structural variation, de novo assembly, and genomic reconstruction. Applications include animal, plant, microbial, viral, and plasmid sequencing for basic, translational, and applied research.

Resources: Illumina-compatible Genome Sequencing • PacBio HiFi Sequencing • Oxford Nanopore Sequencing

Profile microbial communities and targeted genomic regions using short- and long-read sequencing approaches. Applications include microbiome analyses, taxonomic profiling, biodiversity studies, environmental monitoring, genome editing validation, and targeted gene analysis.

Resources: MiSeq • AVITI • PromethION P2 • Fluidigm • BioMark HD

Generate high-quality sequencing data for bulk, spatial, and single cell genomics studies. Access a comprehensive portfolio of short- and long-read sequencing technologies for projects ranging from small targeted studies to large-scale genomic researches.

Resources: AVITI • MiSeq • PromethION P2 • Access to NextSeq 2000, NovaSeq X, and PacBio Revio

Ensure sample quality with nucleic acid quantification and quality assessment. Support library prep, and high-throughput assay development. Robust quality control is prerequisite for successful genomics studies.

Resources:  Agilent 4200 TapeStation • Agilent 2100 Bioanalyzer • NanoDrop • Qubit Fluorometer • BioRuptor • QuantStudio 5 qPCR System • BioMark HD • Fluidigm • NanoString nCounter