To maintain and survey the health of colony rodents housed within LARC, animal housing racks are evaluated at least once a quarter. Our current monitoring system is via Exhaust Air Dust (EAD) testing. Media (filter) material is placed in each rack which captures dust particles flowing through the exhaust. The media remains for the duration of the health monitoring interval, generally 13-16 weeks. At time of testing, the media is removed and submitted to diagnostic laboratories for PCR analysis. As necessary to confirm results, we will sample directly from animals/cages (via PCR) in the rack(s). Other tests and or testing methods, including live sentinels will be utilized on a as needed basis. Tests listed under quarterly and yearly testing are covered by per diems.
Quarterly
Mouse & Rat Prevalent PCR Panel
Mosue |
Rat |
Bacteria Helicobacter Genus (H. spp.) - Helicobacter |
Bacteria Helicobacter Genus (H. spp.) - Helicobacter |
Fungus Pneumocystis murina (P. murina) - Pneumocystis Pneumocystis carinii (P. carinii) - Pneumocystis |
Fungus Pneumocystis murina (P. murina) - Pneumocystis Pneumocystis carinii (P. carinii) - Pneumocystis |
Parasite Entamoeba spp. (Entamoeba) - Endoparasites Radfordia ensifera (R. ensifera) - Ectoparasites Radfordia affinis (R. affinis) - Ectoparasites Pinworms (Pinworms) - Endoparasites Myocoptes musculinus (M. musculinus) - Ectoparasites Myobia musculi (M. musculi) - Ectoparasites Mites (Mites) - Ectoparasites Spironucleus muris (S. muris) - Endoparasites |
Parasite Myobia musculi (M. musculi) - Ectoparasites Mites (Mites) - Ectoparasites Pinworms (Pinworms) - Endoparasites Radfordia affinis (R. affinis) - Ectoparasites Radfordia ensifera (R. ensifera) - Ectoparasites Spironucleus muris (S. muris) - Endoparasites Myocoptes musculinus (M. musculinus) - Ectoparasites |
Virus Murine Norovirus (MNV) - Calicivirus Mouse parvovirus (MPV) - Parvovirus Mouse hepatitis virus (MHV) - Coronavirus Minute virus of mice (MVM) - Parvovirus Group A rotavirus (EDIM) - Reoviruses Theilovirus (RTV) - Picornavirus |
Virus Theilovirus (RTV) - Picornavirus Kilham's Rat Virus (KRV) - Parvovirus Rat minute virus (RMV) - Parvovirus Rat parvovirus (RPV-1) - Parvovirus Sialodacryoadenitis virus, Rat coronavirus (SDAV/RCV) - Coronavirus Toolan's H-1 (H-1) - Parvovirus |
Yearly
Mouse
Surveillance Plus PCR Panel
Bacteria Beta hemolytic Streptococcus Group B (Beta Strep. sp. - Group B) - Beta Strep Proteus mirabilis (P. mirabilis) - Proteus Pseudomonas aeruginosa (P. aeruginosa) - Pseudomonads Klebsiella pneumoniae (K. pneumoniae) - Klebsiella Klebsiella oxytoca (K. oxytoca) - Klebsiella Helicobacter Genus (H. spp.) - Helicobacter Rodentibacter heylii PCR (P. pneumoniae) Rodentibacter pneumotropicas P. Salmonella species (Salmonella spp.) - Salmonella Mycoplasma pulmonis (M. pulmonis) - Mycoplasma Staphylococcus aureus (Staph. aureus) - Staphylococcus Streptobacillus moniliformis (S. moniliformis) - Streptobacillus Corynebacterium kutscheri (C. kutscheri) - Corynebacterium Corynebacterium bovis (C. bovis) - Corynebacterium Clostridium piliforme (CPIL) - Clostridium Citrobacter rodentium (C. rodentium) - Citrobacter Cilia-associated respiratory bacillus (CARB) - Bacillus Campylobacter genus (C. spp.) - Campylobacter Bordetella hinzii (B. hinzii) - Bordetella Bordetella bronchiseptica (B. bronchiseptica) - Bordetella Beta hemolytic Streptococcus Group G (Beta Strep. sp. - Group G) - Beta Strep Beta hemolytic Streptococcus Group C (Beta Strep. zooepidemicus Group C) - Beta Strep Streptococcus pneumoniae (Strep. pneumoniae) - Streptococcus
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Parasite Spironucleus muris (S. muris) - Endoparasites Radfordia affinis (R. affinis) - Ectoparasites Radfordia ensifera (R. ensifera) - Ectoparasites Pinworms (Pinworms) - Endoparasites Myocoptes musculinus (M. musculinus) - Ectoparasites Tritrichomonas genus (Tritrichomonas genus) - Endoparasites Cryptosporidium species (Cryptosporidium spp.) - Protozoa Demodex species (D. aurati) - Ectoparasites Entamoeba spp. (Entamoeba) - Endoparasites Mites (Mites) - Ectoparasites Enteric Protozoa - Other (Enteric Protozoa) - Protozoa Giardia species (Giardia spp.) - Protozoa Myobia musculi (M. musculi) – Ectoparasites
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Fungus Pneumocystis murina (P. murina) - Pneumocystis Pneumocystis carinii (P. carinii) - Pneumocystis
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Virus Orthoreovirus (REO) - Reoviruses Ectromelia (ECTRO) - Poxvirus Sendai virus (SENDAI) - Paramyxovirus Group A rotavirus (EDIM) - Reoviruses Minute virus of mice (MVM) - Parvovirus Pneumonia virus of mice (PVM) - Paramyxovirus Theilovirus (RTV) - Picornavirus Mouse hepatitis virus (MHV) - Coronavirus Mouse parvovirus (MPV) - Parvovirus Murine Norovirus (MNV) - Calicivirus Lymphocytic choriomeningitis virus (LCMV) - Arenavirus Mouse adenovirus-1 (MAV-1) – Adenovirus
|
Yearly
Rat
Surveillance Plus PCR Panel
Bacteria Beta hemolytic Streptococcus Group B (Beta Strep. sp. - Group B) - Beta Strep Pseudomonas aeruginosa (P. aeruginosa) - Pseudomonads Proteus mirabilis (P. mirabilis) - Proteus Rodentibacter heylii PCR (P. pneumoniae) Rodentibacter pneumotropicas P. Mycoplasma pulmonis (M. pulmonis) - Mycoplasma Staphylococcus aureus (Staph. aureus) - Staphylococcus Klebsiella pneumoniae (K. pneumoniae) - Klebsiella Klebsiella oxytoca (K. oxytoca) - Klebsiella Streptobacillus moniliformis (S. moniliformis) - Streptobacillus Helicobacter Genus (H. spp.) - Helicobacter Streptococcus pneumoniae (Strep. pneumoniae) - Streptococcus Salmonella species (Salmonella spp.) - Salmonella Campylobacter genus (C. spp.) - Campylobacter Beta hemolytic Streptococcus Group C (Beta Strep. zooepidemicus Group C) - Beta Strep Corynebacterium kutscheri (C. kutscheri) - Corynebacterium Beta hemolytic Streptococcus Group G (Beta Strep. sp. - Group G) - Beta Strep Clostridium piliforme (CPIL) - Clostridium Cilia-associated respiratory bacillus (CARB) - Bacillus Bordetella bronchiseptica (B. bronchiseptica) - Bordetella
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Parasite Radfordia affinis (R. affinis) - Ectoparasites Pinworms (Pinworms) - Endoparasites Enteric Protozoa - Other (Enteric Protozoa) - Protozoa Spironucleus muris (S. muris) - Endoparasites Myocoptes musculinus (M. musculinus) - Ectoparasites Myobia musculi (M. musculi) - Ectoparasites Radfordia ensifera (R. ensifera) - Ectoparasites Cryptosporidium species (Cryptosporidium spp.) - Protozoa Entamoeba spp. (Entamoeba) - Endoparasites Giardia species (Giardia spp.) - Protozoa Mites (Mites) - Ectoparasites
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Fungus Pneumocystis murina (P. murina) - Pneumocystis Pneumocystis carinii (P. carinii) - Pneumocystis
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Virus Sialodacryoadenitis virus, Rat coronavirus (SDAV/RCV) - Coronavirus Sendai virus (SENDAI) - Paramyxovirus Orthoreovirus (REO) - Reoviruses Rat minute virus (RMV) - Parvovirus Polyomavirus (POLY) - Papovavirus Pneumonia virus of mice (PVM) - Paramyxovirus Theilovirus (RTV) - Picornavirus Mouse adenovirus-1 (MAV-1) - Adenovirus Kilham's Rat Virus (KRV) - Parvovirus Hantavirus Seoul PCR () - Hantavirus Rat parvovirus (RPV-1) - Parvovirus Toolan's H-1 (H-1) – Parvovirus
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Additional health evaluations may be conducted at the discretion of the veterinarian upon consultation with the research staff or according to the specific needs of the investigator. *Additional tests are not covered by per diems and will incur a charge*. Investigators are encouraged to pursue additional tests when their specific research objectives require it.